Gynostemma Pentaphyllum (Jiaogulan): Benefits, Research, and How to Use It

What Is Gynostemma (Jiaogulan)?

Jiaogulan is best known for a class of compounds called gypenosides (also spelled “gypenosidEs” in some literature), which are
saponins—plant compounds that may support multiple systems in the body. Gynostemma contains many different gypenosides,
and some are structurally similar to ginseng’s ginsenosides—one reason you may see it referred to as “Southern Ginseng”.
(It’s not the same plant as Panax ginseng, but it’s discussed in a similar “adaptogen-style” context in some sources.)¹

Many people use Gynostemma as part of a general wellness routine—especially those focused on:

• Cardiometabolic health (heart + metabolism)
• Daily antioxidant support
• Healthy aging
• Stress and energy balance

Top Potential Health Benefits of Gynostemma (What the Research Suggests)

Important note: Human research exists, but it’s not as large or as definitive as research for some vitamins or medications.
Think of these as supportive wellness findings—not promises or disease-treatment claims.

1) Metabolic and Blood Sugar Support

One of the most discussed areas for Jiaogulan is metabolic wellness.
In human research, Gynostemma (often as a tea or extract) has been studied for its potential effects on
insulin sensitivity and blood sugar regulation.²
If you’re building a “metabolic health stack” (diet, movement, sleep, and targeted supplements),
Jiaogulan is a compelling option to consider.

2) Cardiovascular Support (Cholesterol, Circulation, Vascular Health)

Gynostemma is also studied for heart and circulatory support. Research suggests its saponins and related compounds may help support:

• Healthy lipid profiles (cholesterol/triglycerides in normal ranges)
• Healthy blood vessel function and circulation
• Protection from oxidative stress in the vascular system

Reviews and studies have discussed Jiaogulan’s potential cardioprotective actions and its traditional role as a wellness herb.¹

3) Antioxidant Protection and Healthy Aging Support

Oxidative stress is a normal part of metabolism, but when it runs high, it can contribute to “wear and tear” on cells.
Jiaogulan contains antioxidant phytochemicals (including flavonoids and other compounds) that have shown
antioxidant activity in research settings.³

Practically, many customers use Gynostemma to support:

• Daily antioxidant coverage
• Healthy aging routines
• Overall wellness and recovery

4) Adaptogen-Style Stress Support and Energy Balance

Gynostemma is often discussed as an adaptogen-like herb—meaning it may help the body adapt to stressors and support balance.
Reviews describe a broad range of pharmacological actions that align with “resilience” and “recovery” use-cases in everyday wellness.¹

Customers commonly describe their goal as steady, clean daily support (not a stimulant “rush”).
Individual experiences vary, but this is one reason Jiaogulan has stayed popular in traditional tea form.

5) Weight Management and Body Composition (Emerging Area)

Because metabolic health and insulin sensitivity are connected to body composition, Gynostemma has been explored as part of
weight management research. Some studies suggest potential support for metabolic markers relevant to weight regulation,
though results vary by population, dose, and extract type.⁴

Why Standardization Matters: Gypenosides Are the Key

If you compare Jiaogulan products online, you’ll notice a big difference: some list only “Gynostemma powder,” while others specify
a standardized extract. Standardization matters because it helps ensure you get a consistent amount of the bioactive compounds—
especially gypenosides—in each serving.

A standardized 98% gypenosides extract is a “high-potency” approach compared to generic, non-standardized powders—especially if your goal is consistency from bottle to bottle.

How to Take Gynostemma

In studies, doses vary widely depending on the extract type and the intended outcome.
For everyday wellness, many people prefer a simple routine they can stick with.

• Suggested use: Take 1 capsule daily, or as directed by your healthcare professional.
• When: Morning or midday is common for “daily balance” support.
• With or without food: Either is typically fine, but if your stomach is sensitive, take with a meal.

Who Should Be Cautious?

Always check with your clinician if you are pregnant, nursing, have a medical condition, or take medications.
Because Gynostemma is often discussed in relation to metabolism and cardiovascular support, it’s especially important to get medical guidance if you:

• Take blood sugar medications
• Take blood pressure medications
• Use blood thinners or have clotting concerns

This article is for educational purposes and is not medical advice.

FAQ: Jiaogulan (Gynostemma pentaphyllum)

Is Jiaogulan the same as ginseng?

No. Jiaogulan is a different plant from Panax ginseng. It’s sometimes called “Southern Ginseng” because some of its saponins
resemble ginseng’s ginsenosides, and both are discussed in adaptogen-style wellness contexts.¹

How long does it take to notice benefits?

It depends on your goal and your baseline. Some people notice “daily balance” support within a couple of weeks.
Metabolic markers (like fasting glucose or lipids) generally take longer and should be tracked with labs if that’s your focus.

Can I take Jiaogulan with other supplements?

Often yes, but check with your clinician—especially if you’re combining multiple products aimed at metabolic or cardiovascular support.
(Example: berberine + Gynostemma + magnesium, etc.)

Bottom Line

Gynostemma pentaphyllum (Jiaogulan) is a fascinating traditional herb with modern research interest—especially for
metabolic wellness, cardiovascular support, antioxidant protection, and stress resilience.
If you want a consistent, high-potency option, choose a product that’s standardized for gypenosides—
like TerraForm Nutrition’s 98% gypenosides formula.